Publications

 

  1. Huang, Z., Williams, R.B., O'Neil-Johnson, M., Eldridge, G.R., Mangette, J.E., Starks, C.M., "A Total Synthesis of Bifidenone," J.Org.Chem., 2017 82(8),4235-4241
  2. Williams, R., Martin, S., Lawrence, j., Norman, V., O'Neil-Johnson, M., Eldridge, G., Starks, C., "Isolation and Identification of the Novel Tubulin Polymerization Inhibitor Bifidenone," J. Nat. Prod.2016, Accepted, Special Issue in Honor of Professor Phil Crews

  3. Biggs, B., Rouck, J., Kambalyal, A., Arnold, W., Lim, C., De Mey, M., O'Neil-Johnson, M., Starks, C., Das, A., Ajikumar, P., "Orthogonal Assays Clarify the Oxicative Biochemistry of Taxol P450 CYP725A4," ACS Chem. Biol.2016, 11, 1445-1451
  4. Chemler, J.A., Tripathi, A., Hansen, D.A., O'Neil-Johnson, M., Williams, R.B., Starks, C., Park, S.R., Sherman, D.H., Evolution of Efficient Polyketide Synthases by Homologous Recombination, J.Am.Chem.Soc., 2015 137(33), 10603-9

  5. Williams, R.B., O'Neil-Johnson, M., Williams, AlJ., Wheeler, P., Pol, R., Moser, A., Dereplication of Natural Products Using Minimal NMR Data Inputs, Org. Biomol. Chem., 2015 13(39) 9957-62

  6. Zerbe P., Rodriguez S., Mafu S., Chiang A., Sandhu H., O’Neil-Johnson M., Starks C., Bohlmann J., "Exploring Diterpene Metabolism in Non-model Sspecies: Transcriptome-enabled Discovery and Functional Characterization of Labda-7, 13E-Dienyl Diphosphate Synthase from Grindelia robusta," The Plant Journal, 2015, 83, 783-793
     
  7. Augustin, M., Ruzicka, D., Shukla, A., Augustin, J., Starks, C., O'Neil-Johnson, M., McKain, M., Evans, B., Barrett, M., Smithson, A., Wong, G., Deyholos, M., Edger, P., Pires, J., Leebens-Mack, J., Mann, D., Kutchan, T., "Elucidating Steroid Alkaloid Biosynthesis in Veratrum californicum: Production of Verazine in Sf9 Cells," The Plant Journal2015, 82, 991-1003
     
  8. Zerbe, P., Chiang, A., Dullat, H., O'Neil-Johnson, M., Starks, C., Hamberger, B., Bohlmann, J., "Diterpene Synthases of the Biosynthetic System of Medicinally Active Diterpenoids in Marrubium vulgare," The Plant Journal, 2014, 79, 914-927 Identifying Biosynthetic Intermediates at the Microgram Scale 
     
  9. Kilgore, M., Rolf, M., Starks, C.M., O'Neil-Johnson, M., Kutchan, T.M., "Cloning and Characterization of a Norbelladine 4'-O-Methyltransferase Involved in the Biosynthesis of the Alzheimer's Drug Galanthamine in Narcissus spp." PLOS One, 2014, DOI: 10.1371/journal.pone.0103223 - Identifying Biosynthetic Intermediates at the Microgram Scale 
     
  10. Starks, C.M.; Norman, V.L.; Williams, R.B.; Goering, M.G.; Rice, S.M.; O'Neil-Johnson, M.A.; Eldridge, G.R. "Antibacterial Activity of Taxodium ascendens Diterpenes Against Methicillin-resistant Staphylococcus aureus." Natural Product Communications, 2014, 9 (8), 1129-1130
     
  11. La Clair, J., Loveridge, S., Tenney, K., O'Neil-Johnson, M., Chapman, E., Crews, P., "In Situ Natural Product Discovery via an Artificial Marine Sponge." PLOS One, 2014, 9 (7), DOI: 10.1371/journal.pone.0100474
     
  12. Williams, Russell; Du, Lin; Norman, Vanessa; Goering, Matt; O'Neil-Johnson, Mark; Woodbury, Scott; Albrecht, Matthew; Powell, Douglas; Cichewicz, Robert; Eldridge, Gary; Starks, Courtney "Diterpenes from the Endangered Goldenrod Solidago shortii." Journal of Natural Products2014, 77 (6), 1438-1444
     
  13. Starks, C.M.; Williams, R.B.; Norman, V.L.; Rice, S.M.; O'Neil-Johnson, M.A.; Lawrence, J.A.; Eldridge, G.R. "Antibacterial Chromene and Chromane Stilbenoids from Hymenocardia acida." Phytochemistry2014, 98,216-222
     
  14. Williams, Russell; Norman, Vanessa; Goering, Matt; O'Neil-Johnson, Mark; Eldridge, Gary; Starks, Courtney "Acetylated Dammarane-type Bisdesmosides from Combretum inflatum." Journal of Natural Products2013, 76, 1592-1597
     
  15. Williams, R.B.; Martin, S.M.; Hu, J.F.; Norman, V.L.; Goering, M.G.; Loss, S.; O'Neil-Johnson, M.A.; Eldridge, G.R.; Starks, C.M. "Cytotoxic and Antibacterial Beilschmiedic Acids from a Gabonese Species of Beilschmiedia." Journal of Natural Products, 2012, 75, 1319-1325
     
  16. Starks, C.M.; Williams, R.B.; Norman, V.L.; Lawrence, J.A.; O'Neil-Johnson, M.A.; Eldridge, G.R. "Phenylpropanoids from Phragmipedium calurum and their Antiproliferative Acitivity." Phytochemistry2012, 82, 172-175
     
  17. Starks, C.M.; Williams, R.B.; Rice, S.M.; Norman, V.L.; Lawrence, J.A.; Goering, M.G.; O'Neil-Johnson, M.; Hu, JF; Eldridge, G.R. "Cytotoxic Cyclohexene Derivatives from Monanthotaxis congoensis." Phytochemistry2012, 74185-189
     
  18. Williams, R.B.; Martin, S.M.; Hu, J.F.; Garo, E.; Rice, S.M.; Norman, V.L.; Lawrence, J.A.; Hough, G.W.; Goering, M.G.; O'Neil-Johnson, M.A.; Eldridge, G.R.; Starks, C.M. "Isolation of Apoptosis-Inducing Stilbenoids from Four Members of the Orchidaceae Family." Planta Medica, 2012, 78(2), 160-165
     
  19. Olson, K.M.; Starks, C.M.; Williams, R.B.; O'Neil-Johnson, M.; Huang, Z.; Ellis, M.; Reilly, J.; Eldridge, G.R. "Novel Pentadecenyl Tetrazole Enhances Susceptibility of MRSA Biofilms to Gentamicin", Antimicrobial Agents and Chemotherapy2011, 55(8) 3691-3695
     
  20. Starks, C.M; Williams, R.B.; Norman, V.L.; Lawrence, J.; Goering, M.G.; O'Neil-Johnson, M.; Hu, J.F.; Rice, S.M.; Eldridge, G.R. Abronione, a rotenoid from the desert annual Abronia villosaPhytochemistry Letters2011, 4, 72-74
     
  21. Williams, R.B.; Hu, J.F.; Olson, K.M.; Norman, V.L.; Goering, M.G.; O'Neil-Johnson, M.; Eldridge, G.R.; Starks, C.M. Antibiotic Indole Sesquiterpene Alkaloid from Greenwayodendron suaveolens with a New Natural Product Framework. Journal of NaturalProducts2010, 73, 1008-1011
     
  22. Ye, M.; Zhao, Y.; Norman, V.L.; Starks, C.M.; Rice, S.M.; Goering, M.G.; O'Neil-Johnson, M.; Eldridge, G.R.; Hu, JF. Antibiofilm phenylethanoid glycosides from Penstemon centranthifoliusPhytother Res2010, 24(5), 778-81
     
  23. Starks, C.; Williams, R.B.; Goering, M.G.; O'Neil-Johnson, M.; Norman, V.L.; Hu, J.F.; Garo, E.; Hough, B.; Rice, S.M.; Eldridge, G.R. Antibacterial Clerodane Diterpenes from SolidagovigaureaPhytochemistry2010, 71, 104-109
     
  24. Fan, H., Starks, C.M., Hughey, H., Eldridge, G.R., Hu, J.F. Natural anti-HCV Agents, Drugs of the Future, 2009, 34(3), 223-236
     
  25. Garo, E.; Huang, C.S.; Williams, R.B.; Olson, K.M.; Hu, J.F.; Rice, S.M.; Hough, B.; Goering, M.G.; O'Neil-Johnson, M.; Eldridge, G.R. Dammarane-Type Triterpene Glycosides from Oncoba manii Active against Methicillin-Resistant Staphylococcus aureus. Planta Medica2009, 75, 541-543
     
  26. Hu, J.F.; Starks, C.; Williams, R.B.; Rice, S.M.; Norman, V.L.; Olson, K.M.; Hough, B.; Goering, M.G.; O'Neil-Johnson, M.; Eldridge, G.R. Secoiridoid Glycosides from the Pitcher Plant Sarracenia alataHelvetica Chimica Acta2009, 92, 273-28
     
  27. Hu, J.F.; Eldridge, G.R.; Yu, Y.H.; O'Neil-Johnson, M. High-throughput Natural Product Chemistry Methods and the Application of the Capillary NMR Probe, Prog. Chem., 2008,20 (4), 429-440
     
  28. Hu, J.F.; Starks, C.; Garo, E.; Hough, G.; Rice, S.; Goering, M.G.; O'Neil-Johnson, M.; Eldridge, G.R. Laxanol, a new 2,5-diaryl-3,4-dihydroxymethyltetrahydrofuran type lignan from Justicia laxaJournal of Chemical Research2008, 1, 20-21
     
  29. Cegelski, L.; Marshall, G.R.; Eldridge, G.R.; Hultgren, S.J. The Biology and Future Prospects of Antivirulence Therapies, Nature Rev. Microbiol. 2008, 6, 17-27
     
  30. Garo, E.; Eldridge, G.R.; Goering, M.; DeLancey Pulcini, E.; Hamilton, M.; Costerton, J.; James, G. Asiatic Acid and Corosolic Acid Enhance the Susceptibility of Pseudomonas aeruginosa Biofilms to Tobramycin. Antimicrob. Agents Chemother., 2007, 51, 1813-1817
     
  31. Hu, J.F.; Garo, E.; Hough, G.; Goering, M.; O’Neil-Johnson, M.; Eldridge, G.R.
    Acuminatanol, the first 2',2'''-bis-dihydrobiflavonol from the Aqueous Extract of Trichoscypha acuminata; Tetrahedron Letters2007, 48, 5747-5749
     
  32. Hu, J.F.; Garo, E.; Hough, G.; Goering, M.; Yoo, H.D; O’Neil-Johnson, M.; Eldridge, G.R.
    Isoflavones from Psorothamnus arborescens via High-throughput Natural Product Chemistry Methods; Journal of Chemical Research2007, 5, 296-297
     
  33. Garo, E.; Hu, J.F.; Hough, G.; Goering, M.; O’Neil-Johnson, M.; Eldridge, G.R. Stilbenes from the Orchid Phragmipedium sp. Journal of Natural Products2007, 70, 968-973
     
  34. Hu, J.F.; Patel, R.; Li, B.; Garo, E.; Hough, G.; Goering, M.; Yoo, H.D.; O’Neil-Johnson, M.; Eldridge, G.R. Anti-HCV Bioactivity of Pseudoguaianolides from Parthenium hispitumJournal of Natural Products2007, 70, 604-607
     
  35. Hu, J.F.; Garo, E.; Hough, G.W.; Goering, M.G.; O’Neil-Johnson, M.; Eldridge, G.R. Antibacterial, Partially Acetylated Oligorhamnosides from Cleistopholis patensJ.Nat. Prod.200669, 585-590
     
  36. Hu, J.F.; Garo, E.; Goering, M.G.; Pasmore, M.; Yoo, H.D.; Esser, T.; Sestrich, J.; Cremin, P.C.; Hough, G.W.; Perrone, P.; Lee, Y.; Le, N.; O’Neil-Johnson, M.; Costerton, J.W.; Eldridge, G.R. Bacterial Biofilm Inhibitors from Diospyros dendo. J. Nat. Prod. 200669, 118-120
     
  37. Hu, J.F.; Garo, E.; Yoo, H.D.; Cremin, P.A.; Goering, M.G.; O’Neil-Johnson, M.; Eldridge, G.R. Cyclolignans from Scyphocephalium ochocoa via high-throughput natural product chemistry methods. Phytochemistry200566, 1077-1082
     
  38. Peti, W.; Page, R.; Moy, K.; O’Neil-Johnson, M.; Wilson, I.A.; Stevens, R.C.; and Wüthrich, K. Towards Miniaturization of a Structural Genomics Pipeline Using Micro-expression and Microil NMR. J.Struct.Funct.Genomics20056, 259-267
     
  39. Ren, D.; Zuo, R.; Gonzalez, A.F.; Bedzyk, L.A.; Eldridge, G.R.; Pasmore, M.E.; Wood, T.K. Differential Gene Expression for Investigation of Escherichia coli Biofilm Inhibition by Plant Extract Ursolic Acid. Appl. Environ. Microbiol. 200571, 4022-4034
     
  40. Hu, J.F.; Garo, E.; Yoo, H.D.; Cremin, P.A.; Zeng, L.; Goering, M.G.; O’Neil-Johnson, M.; Eldridge, G.R. Application of capillary-scale NMR for the structure determination of phytochemicals. Phytochem. Anal. 200516, 127-133
     
  41. Yoo, H.D.; Cremin, P.A.; Zeng, L.; Garo, E.; Williams, C.T.; Lee, C.M.; Goering, M.G.; O'Neil-Johnson, M.; Eldridge, G.R.; Hu, J.F. Suaveolindole, a New Mass-Limited Antibacterial Indolosesquiterpene from Greenwayodendron suaveolens Obtained via High-Throughput Natural Products Chemistry Methods. J.Nat.Prod. 200568, 122-124
     
  42. Hu, J.F.; Yoo, H.D.; Williams, C.T.; Garo, E.; Cremin, P.A.; Zeng, L.; Vervoort, H.C.; Lee, C.M.; Hart, S.M.;Goering, M.G.; O’Neil-Johnson, M.; Eldridge, G.R. Miniaturization of the Structure Elucidation of Novel Natural Products – Two Trace Antibacterial Acylated Caprylic Alcohol Glycosides from Arctostaphylos pumilaPlanta Med200571, 176-180
     
  43. Olson, D.L.; Norcross, J.A.; O'Neil-Johnson, M.; Molitor, P.F.; Detlefsen, D.J.; Wilson, A.G.; and Peck, T.L. Microflow NMR: Concepts and Capabilities. Anal. Chem. 200476, 2966-2974
     
  44. Peti, W.; Norcross, J.; Eldridge, G.R.; O’Neil-Johnson, M. Biomolecular NMR Using a Microcoil NMR Probe – New Technique for the Chemical Shift Assignment of Aromatic Side Chains in Proteins. J. Am. Chem. Soc. 2004126, 5873-5878
     
  45. Cremin, P.A.; Zeng, L. High-Throughput Analysis of Natural Product Compound Libraries by Parallel LC-MS Evaporative Light Scattering Detection. Anal. Chem. 200274, 5492-5500
     
  46. Eldridge, G.R.; Vervoort, H.C.; Lee, C.M.; Cremin, P.A.; Williams, C.T.; Hart, S.M.; Goering, M.G.;O’Neil-Johnson, M.; Zeng, L. High-Throughput Method for the Production and Analysis of Large Natural Product Libraries for Drug Discovery. Anal. Chem. 200274, 3963-3971