Sequoia uses the most advanced NMR technologies to rapidly generate spectroscopic data for structure determination. Utilizing the TCI 1.7 MicroCryoProbe™ technology in a scientific collaboration with Bruker Biospin, Sequoia can rapidly elucidate the structures of biologically-active compounds on microgram quantities of material.

 

Less than 10 micrograms of material (90% purity) is needed to acquire 1-D proton and 2-D HSQC data sets. Less than 20 micrograms of material (90% purity) is needed to acquire an HMBC data set.

HMBC on 2 micrograms of a novel indoloesesquiterpene from Greenwayodendron suaveolens
(Journal of Natural Products, 2005, 68, 122-124)

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Other Examples of NMR Spectra

Proton: 2 micrograms of Suaveolindole in 14 microliters MeOH,d₄

(J.Nat.Prod. 2005, 68, 122-124)

HSQC: 2 micrograms of Suaveolindole in 14 microliters MeOH,d₄

HSQC: 10 micrograms of Suaveolindole in 14 microliters Methanol-d₄

HMBC: 10 micrograms of Suaveolindole in 14 microliters Methanol-d₄

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