Sequoia Sciences
Sequoia Sciences Sequoia Sciences
High-throughput Natural Products Chemistry

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Sequoia Sciences has an unparalleled collection of structurally diverse natural product compounds isolated from plants.  From this collection, Sequoia has identified compounds that may potentially provide alternative treatments for chronic infections involving bacterial biofilms.

Based upon these results, Sequoia Sciences is embarking on a pre-clinical development program with the goal of addressing the unmet medical need for the treatment of Pseudomonas aeruginosa lung infections in Cystic Fibrosis patients.  Our goal is to improve the quality of life for those individuals significantly affected by chronic bacterial infections.   To this purpose, we are engaged in multiple collaborations with other laboratories and universities.

Recent Publications | See All

Jan. 2008: The Biology and Future Prospects of Antivirulence Therapies, Nature Rev. Microbiology

May, 2007: Asiatic Acid and Corosolic Acid Enhance the Susceptibility of Pseudomonas aeruginosa Biofilms to Tobramycin, Antimicrobial Agents and Chemotherapy

May, 2007: Stilbenes from the Orchid Phragmipedium sp., Journal of Natural Products